ME 6782: Cellular Engineering
Offered Every Fall

Credit Hours: 3-0-3
Prerequisite: Graduate standing in engineering or related discipline
Catalog Description: Engineering analysis of the cellular systems, Crosslisted with BMED and CHE 6782.
Textbooks:

Bruce Alberts, Julian Lewis, Alexander Johnson, and M. Raff, Molecular Biology of the Cell (w/CD), 4th Edition, Taylor & Francis, 2002.
Instructors: Andres Garcia (Fall 2004), Cheng Zhu (Fall 2003, Fall 2004) and guest lecturers

Methods of Evaluation:

Topics:

  • Cellular structures and organizations
  • Membrane, the nucleus, organelles, cytoskeleton, and ECM
  • Cellular functions and their control
  • Proteins and enzymes
  • DNA, RNA, and recombinant DNA Technology
  • The cell as an engineering system
  • Mathematical modeling of calcium transient
  • Mechanical properties of cells
  • Experiments
  • Analyses
  • Cell adhesion
  • Adhesion molecules
  • Intercellular and interfacial forces
  • Mechanical and thermodynamic models
  • Kinetic and transport models
  • Cell locomotion
  • Molecular motors
  • Forces generated by a cell and a motor molecule
  • Models of cell locomotion
  • Other receptor-mediated processes
  • Binding, trafficking and signaling

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    Revised June 2004