Publications

Publications

from the

Georgia Tech Vascular and Biofluids Research Group

PUBLISHED BOOKS AND PARTS OF BOOKS

  1. Giddens, D.P., Zarins, C.K., Glagov, S., Bharadvaj, B.K., Ku, D.N., "Flow and atherogenesis in the human carotid bifurcation," in Fluid Dynamics as a Localizing Factor for Atherogenesis, (D. Schettler, et al., eds.) Berlin:  Springer-Verlag  pp. 38-45, 1983.
  2. Giddens, D.P., Bharadvaj, B.K., Ku, D.N., "Cerebral and peripheral hemodynamics, " in Cardiovascular Ultrasonic Flowmetry, eds. S.A., Altobelli, W.F. Voyles, E.R. Greene, Elsevier, New York, pp. 125-147, 1985.
  3. Ku, D.N., Zarins, C.K., Giddens, D.P., Glagov, S., "Separated and secondary flow and early atherosclerosis in the human carotid bifurcation," in Role of Blood Flow in Atherogenesis,  (Y. Yoshida, et al, eds.) Tokyo, Springer-Verlag, pp. 73-80, 1988.
  4. Glagov, S., Zarins, C.K., Giddens, D.P., Ku, D.N. "Hemodynamic determinants of the breaking train, configuration, composition and complication of human atherosclerotic plaques," in Role of Blood Flow in Atherogenesis, pp. 3-10, 1988.
  5. Giddens, D.P., Zarins, C.K., Ku, D.N., Glagov, S., "The utility of correlations between made flow studies and vessel pathology in describing atherosclerosis," in Role of Blood Flow in Atherogenesis, pp. 63-66, 1988.
  6. Zarins, C.K., Glagov, S., Giddens, D.P., Ku, D.N. "Hemodynamic factors and atherosclerotic change in the aorta," in Aortic Surgery:  New Diagnostic and Operative Techniques, (J.J. Bergan and  J.S.T. Yao Eds.) Chicago:  W.B. Saunders Co.  pp. 17-26, l988.
  7. Glagov, S., Bassiouny, H., Masawa, N., Ku, D.N., Vito, R.P. Giddens, D.P., Zarins, C.K. "Hemodynamic and structural determinants of human plaque stability," in Atherosclerosis VIII, (G. Crepaldi et al, eds) Amsterdam, Elsevier Science Publ pp. 411-415, l989.
  8. Glagov, S., Zarins, C.K., Giddens, D.P., Ku, D.N., "Mechanical factors in the pathogenesis, localization and evolution of atherosclerotic plaques" in Diseases of the Arterial Wall, (Springer-Verlag, N.Y.), pp. 2l7-239, l989.
  9. Ku, D.N., Zeigler M., Stewart, M., "A study of predicted and experimental wall collapse in models of highly stenotic arteries." in 2nd International Symposium on Biofluid Mechanics,(D. Liepsch, ed) Munich, Karger Scientific Publ., pp. 409-416, l989.
  10. Poiseau, E., Yoganathan, A., Ku, D.N., Dixon, T., "Magnetic resonance imaging of cardiac blood flow:  An in vitro study." in 2nd International Symposium on Biofluid Mechanics, (D. Liepsch, ed) Munich, Karger Scientific Publ., pp. 241-248, l989.
  11. Ku, D.N., Peifer, J., Biancheri, C., Pettigrew, R.I., Engels, H. "Potential Value of Magnetic Resonance Angiography in Patients with Vascular Disease", in Current Critical Problems in Vascular Surgery (F.J. Veith, ed), Vol. II, pp. 36-4l, l990.
  12. Ku, D.N., Zhu, C., "The mechanical environment of the artery," in Hemodynamic Forces and Vascular Cell Biology, (Sumpio B. ed.), Austin, R. G. Landes Co., pp. 1-23, 1993.
  13. Ku, D.N., Lumsden, A., "Blood Flow Patterns in Cardiovascular Disease," in Vascular Disease:  Surgical and Interventional Therapy (D.E.Strandness, Jr. ed.), New York, Churchill Livington, pp 73-83, 1994.
  14. Ku, D.N., Powell, B.E., Downing, J.M.  "Contribution of flow choking to dynamic stenosis resistance", in 3rd International Symposium on Biofluid Mechanics and Biorheology, VDI  Verlag, D¸sseldorf, 1994.
  15. Ku, D.N., Allen, R.C., "Vascular Grafts," in The Biomedical Engineering Handbook (Bronzino, J.D., ed.), Boca Raton, FL, CRC Press, Inc., pp. 1871-1878, 1995.
  16. Ku, D.N., "Blood Flow in Arteries," in Annual Review of Fluid Mechanics, Annual Reviews, Inc., Vol. 29, pp. 399-434, 1997.
  17. Ku, D.N., Nerem, R.M., "Hemodynamic influences on vascular injury, repair and remodeling," in Comprehensive Toxicology, (I.G. Sipes, C.A. McQueen, A.J. Gandolfi, eds.), New York, NY Elsevier Science, Inc., pp 241-253, 1997.

PUBLISHED JOURNAL PAPERS (REFEREED)

  1. Churchill, F.C., Ku, D.N., Miles, J.W., "Gas-liquid chromatographic inlet block derivation of organophosphorus pesticides and related dialkyl phosphothiolates," Journal of Agriculture and Food Chemistry, vol. 26, no. 5, pp. 1108-1112, 1978.
  2. Churchill, F.C., Ku, D.N., "Extractive alkylation of 5.2'-dicholoro-4' nitrosalicylanilide (Niclosamide) for gas-liquid chromatographic analysis," Journal of Chromatography, vol. 189, pp. 375-388, 1980.
  3. Ku, D.N., Green, P.R., "Scleral creep in vitro resulting from cyclical pressure pulses:  application to myopia," Am. J. Optom. and Physiol. Optics, vol. 58, pp. 528-535, 1981.
  4. Ku, D.N., "Cell electrophoresis in percoll density gradients," Separation and Purification Methods, vol. 11, pp. 71-82, 1982.
  5. Ku, D.N. Giddens, D.P., "Pulsatile flow visualization at the carotid branch," Arteriosclerosis, vol. 3, pp. 31-39, 1983.
  6. Ku, D.N., Phillips, D.J., Giddens, D.P., Strandness, D.E., "Hemodynamics of the normal human carotid bifurcation in vitro and in vivo studies," Ultrasound in Medicine and Biology, no. 11, pp. 13-26, 1985.
  7. Ku, D.N., Giddens, D.P., Zarins, C.K., Glagov, S., "Pulsatile flow and atherosclerosis in the human carotid bifurcation," Arteriosclerosis, vol. 5, pp. 293-302, 1985.
  8. Ku, D.N., Liepsch, D., "The effects of non-Newtonian viscoelasticity and wall elasticity on flow at a 90 degree bifurcation," Biorheology, vol. 23, pp. 359-370, 1986.
  9. Giddens, D.P., Ku, D.N., "A note on the relation between input flow waveform and wall shear rate in pulsatile separating flows," J. Biomechanical Engineering vol. 109, 175-176, 1987.
  10. Ku, D.N., Giddens, D.P., "Laser Doppler anemometer measurements of pulsatile flow in a model carotid bifurcation," J. Biomechanics, vol. 20, pp. 407-21, 1987.
  11. Zarins, C.K., Zatina, M.A., Giddens, D.P., Ku, D.N., Glagov, S, "Shear stress regulation of artery lumen diameter in experimental atherosclerosis," J. Vascular Surgery, vol. 5, pp. 413-420, 1987.
  12. Ku, D.N., Klafta, J.M., Gewertz, B.L., Zarins, C.K., "The Contribution of Valves to Saphenous Vein Graft Resistance," J. Vascular Surgery, vol. 6, pp. 274-279, 1987.
  13. Ku, D.N., "A Review of Carotid Duplex Scanning," Echocardiography, vol. 5, pp. 53-69, 1988.
  14. Holenstein, R., Ku, D.N., "Reverse flow in the major infrarenal vessels - A capacitive phenomenon," Biorheology, vol. 25, pp. 835-842, 1988.
  15. Ku, D.N., Ma, P.P., McConnel, F.M.S. Cerenko, D., "Frame by frame analysis of swallowing using manofluorography," Surgical Forum, vol. 39, pp. 545-548, 1988.
  16. Glagov, S., Zarins, C.K., Giddens, D.P., Ku, D.N., "Hemodynamics and Atherosclerosis, Insights and perspectives gained from studies of human arteries,"  Archives of Pathology and Laboratory Medicine, Vol. 112, pp. 1018-1031, 1988.
  17. Ku, D.N., Glagov, S., Moore, J.E., Zarins, C.K., "Flow patterns in the abdominal aorta under simulated postprandial and exercise conditions," J. Vascular Surgery, vol. 9, pp. 309-316, 1989.
  18. Oweida, S.W.,  Ku, D.N., Kam, C.M., Powers, J.C., "In vivo testing of a new synthetic anticoagulant compound",  Surgical Forum, Vol. 40, pp. 318-320, 1989.
  19. Binns, R.L., Ku, D.N., "The effect of stenosis on wall motion:  A possible mechanism of stroke and transient ischemic attack." Arteriosclerosis, Vol. 9, pp. 842-847, 1989.
  20. Binns, R.L., Ku, D.N., Stewart, M.T., Ansley, J.P., Coyle, K.A., "Optimal Graft Diameter:  Effect of wall shear stress on vascular healing". J. Vascular Surgery, Vol. 10, pp. 326-37, 1989.
  21. Oweida, S.W.,  Ku, D.N., Kam, C.M., Powers, J.C., "In vivo determination of the anticoagulant effect of a substituted isocoumarin", Thrombosis Research, Vol. 58, 191-197, 1990.
  22. Ku, D.N., Zeigler, M.N., Downing, J.M., "One-dimensional steady inviscid flow through a stenotic collapsible tube," J. Biomechanical Engineering, Vol. ll2, pp. 444-450, 1990.
  23. Ku, D.N., Biancheri, C., Peifer, J., Markou, C., Engels, H., Pettigrew, R.I., "An evaluation of magnetic resonance velocimetry for steady flow", Journal of Biomechanical Engineering, Vol. ll2, pp.464-472, 1990.
  24. Ku, D.N., Ma, P.P., McConnel, F.M.S., Cerenko, D., "A kinematic study of oropharyngeal swallowing of a liquid," Annals of Biomedical Engineering, pp. 655-669,  1990.
  25. Oweida, S.W., Ku, D.N., Justicz, A.G., Burnson, G., Salam, A.A., "Hemodynamic consequences of carotid-carotid bypass for innominate artery stenosis." Journal of Vascular Surgery, Vol. 13; pp. 416-422, 1991.
  26. McKinsey, J., McCord, B.N., Aoki, T., Ku, D.N.  "Can mechanical stress cause fatigue of the atherosclerotic plaque"?  Surgical Forum, Vol 42: pp.318-19, 1991.
  27. Markou, C., Ku, D.N.  "Accuracy of velocity measurements using pulsed Doppler ultrasound:  A comparison between five signal analysis techniques,"  Ultrasound in Medicine and Biology, Vol. 17, pp. 803-814, 1991.
  28. Moore, J.E., Jr., Ku, D.N., Zarins, C.K., Glagov, S.  "Pulsatile flow visualization in the abdominal aorta under differing physiologic conditions:  Implications for increased susceptibility to atherosclerosis," J. Biomechanical Engineering, Vol 114, pp. 391-97, August, 1992.
  29. Salam, T.A., Lumsden, A.B., Suggs, W.D., Ku, D.N. "Effects of wall shear stress and graft orientation on vascular healing of tapered grafts," Surgical Forum, Vol 43, 332-336, 1992.
  30. Oshinski, J.N., Ku, D.N., Bohning, D.E., Pettigrew, R.I. "The effects of acceleration on the accuracy of MR phase velocity measurements, Journal of Magnetic Resonance Imaging, Vol. 2, pp 665-670, November/December 1992.
  31. He, X., Ku, D.N., Moore, J.E., Jr.  "Simple calculation of the velocity profiles for pulsatile flow in a blood vessel using Mathematica," Annals of Biomedical Engineering, Vol. 21:1, pp. 45-50, January/February 1993.
  32. Reneman, R.S., Hoeks, A.P.G., van de Vosse, F., Ku, D.N. "Three-dimensional blood flow in bifurcations- Computational and experimental analyses and clinical applications," Cerebrovascular Diseases, Vol. 3, pp 185-192, 1993.
  33. Aoki, T., Ku, D.N. "Collapse of diseased arteries with eccentric cross-section," Journal of Biomechanics, Vol. 26:2, pp 133-42, 1993.
  34. Peifer, J.W., Ku, D.N., "Computer modelling of the abdominal aorta using magnetic-resonance images," Annals of Biomedical Engineering, Vol. 21:2, pp 237-46, 1993.
  35. Moore, J.E., Ku, D.N. "Pulsatile velocity measurements in a model of the human abdominal aorta under resting conditions," Journal of Biomechanical Engineering, Vol. 116:337-346, 1994.
  36. Moore, J.E., Ku, D.N. "Pulsatile velocity measurements in a model of the human abdominal aorta under simulated exercise and postprandial conditions," Journal of Biomechanical Engineering, Vol. 116, No. 1, 107-111, 1994.
  37. Siegel, J., Markou, C.K., Ku, D.N.  "A Scaling Law for Wall Shear Rate Through an Arterial Stenosis," Journal of  Biomechanical Engineering, Vol. 116:446-451, 1994.
  38. He, X., Ku, D.N. "Unsteady entrance flow development in a straight tube."  Journal of Biomechanical Engineering, Vol. 116:355-360,  1994.
  39. Moore, J.E., Xu, C., Glagov, S., Zarins, C.K., Ku, D.N.  "Fluid wall shear stress measurements in a model of the human abdominal aorta: Oscillatory behavior and relationship to atherosclerosis." Atherosclerosis, 110:225-240, 1994.
  40. Moore, J.E., Maier, S.E., Ku, D.N., Boesiger, P.  "Hemodynamics in the abdominal aorta:  A comparison of in vitro and in vivo measurements." Journal of Applied Physiology, vol 76(4): 1520-27, 1994.
  41. Ma, P., Li, X., Ku, D.N.  "Heat and mass transfer in a separated flow region for high Prandtl and Schmidt numbers under pulsatile conditions".  Int J Heat and Mass Transfer Vol 37:17; 2723-2736, 1994.
  42. Chen, C., Suwyn, C., Mattar, S., Coyle, K.A., Ku, D.N., Lumsden, A.B.  "Distribution of tenascin in human neointimal hyperplastic lesions," Surgical Forum, Vol. XLV, 382-385, 1994.
  43. Oshinski, J.O., Ku, D.N., Pettigrew, R.I. "Turbulent velocity fluctuations:  The principle determinant of post stenotic signal loss," Magnetic Resonance in Medicine, Vol. 33:2, 193-199, 1995.
  44. He, X, Ku, D.N.,  "Flow in T-Bifurcations:  Effect of the sharpness of the flow divider",  Biorheology  32:(4), 447-458, 1995.
  45. Oshinski, J.O., Ku, D.N., Loth, F., Mukundan, S., Pettigrew, R.I. "Determination of wall shear stress in the abdominal aorta using MR phase velocity mapping", Journal of Magnetic Resonance Imaging, 5:640-647, 1995.
  46. Siegel, J.M., Jr., Oshinski, J.N., Pettigrew, R.I., Ku, D.N., "Comparison of phantom and computer simulated magnetic resonance images of flow in a convergent geometry:  Implications for improved 2D MR angiography", Journal of Magnetic Resonance Imaging, 5:677-683, 1995.
  47. Siegel, J.M., Oshinski, J.N., Pettigrew, R.I., Ku, D.N., "The accuracy of magnetic resonance phase velocity measurements in stenotic flow," Journal of  Biomechanics, 29:12, 1665-1672; December 1996.
  48. He, X., Ku, D.N., "Pulsatile flow in the human left coronary artery bifurcation:  Average conditions", Journal of Biomechanical Engineering, 118:74-82, 1996.
  49. Salam, T.A., Lumsden, A.B., Suggs, W.D., Ku, D.N.  "Low shear stress promotes intimal hyperplasia in a dose-response manner," Journal of Vasc. Investig. 2:1, 12-22, March 1996.
  50. Chen, C. Ku, D.N., Kikeri D., Lumsden A.E.,  "Tenacin:  A potention role in human arteriovenous PTFE graft failure", J. Surg. Research, 60:409-416, 1996.
  51. Chen, C., Coyle, K. A., Hughes, J.D., Mattar, S.G., Lumsden, A.B., Ku, D.N.; "Reduced Blood Flow Accelerates in Endarterectomized Canine Arteries".  Cardiovascular Surg,  Vol. 5:2, 161-168, April 1997.
  52. Chen, C., Mattar S.G., Hughes, J.D., Hanson, S.R., Ku, D.N., Lumsden, A.B., "Recombinant Mitotoxin Basic FGF-Saporin Reduces Venous Intimal Hyperplasia."  Circulation  Vol 94:8, 1989-1995, October 15, 1996.
  53. Chen, C., Hanson, S.R., Keefer, L., Hutsell, T., Hughes, J.D., Mattar, S.G., Ku, D.N., Lumsden, A.B.  "Boundary Layer Infusion of Nitric Oxide Reduces Smooth Muscle Cell Proliferation of Injured Arteries in a Canine Model".  Journal of  Surgical Research, Vol. 67:1, January, 1997.
  54. Chen, C., Hughes, J.D., Mattar, S.G., Ku, D.N., Lumsden, A.B., "Time-Course Study of Intimal Hyperplasia in the Endarterectomized Canine Artery", Journal of Surgical Research, Vol. 67:1,  106-112, January 1997.
  55. Siegel JM, Oshinski JN, Pettigrew RI, Ku DN. "Computational Simulation of Turbulent Signal Loss in 2D Time-of-Flight Magnetic Resonance Angiograms." Magnetic Resonance in Medicine, Vol. 37, pp 609-614, 1997.
  56. Oshinski, J.O., Parks, W.J., Markou, C.P., Bergman, H.L., Larson, B.E., Ku, D.N., Mukundan, S, Pettigrew, R.I. "Improved Measurement of Pressure Gradients in Aortic Coarctation by Magnetic Resonance Imaging." American College of Cardiology, 28:7, 1818-26, December 1996.
  57. Downing, J.M., Ku, D.N.  "Effects of Frictional Losses and Pulsatile Flow in the Collapse of Stenotic Arteries," J Biomech Engng, Vol. 119:3, 317-324, August 1997.
  58. Ma, P., Li, X., Ku, D.N.  "Convective mass transfer at the carotid bifurcation", J. Biomechanics, Vol. 30:6, 565-571, 1997.
  59. He, X., Ku, D.N. "The importance of variations in branch angle changes on the hemodynamics of the left coronary artery", J. Biomech., (in submission).
  60. Biz, S., Ku, D.N.  "Experimental flow choking in a model of a collapsible stenosis", J. Biomech. Engng. (in submission).
  61. DeWeese, F.T., Eldridge, J.C., Ku, D.N., He, X.  "Ilizarov correction of deformity:  A method to simplify and optimize planning," (in submission).
  62. Moore, J.E., Golay, X., Ku, D.N., Stergiopulos, N., Meister, J.J. "Velocity profiles in the collapsed region of an elastic stenosis", Annals of Biomed Engng (in submission).
 
 

For information on our research, please send e-mail to david.ku@me.gatech.edu , phone us at 404 894-6827, or FAX us at 404 894-2291.


Back to
Georgia Tech Vascular and Biofluids Research Group